Do I need to take a second postinor pill. Escapel, Postinor: side effects, analogues

On our planet, it ends with an interruption. In one case, this happens regardless of the desire of the woman. At the same time, the average period for which a miscarriage occurs (natural or artificial) is up to eight weeks. Also, an interruption can occur at the request of the fairer sex. One of the ways to have an abortion is to use the drug "Postinor". For the early stages, it is quite effective. However, some women use it after a missed period. This article will tell you about whether Postinor can terminate a pregnancy in the early stages. You will learn how to use this medication and the opinions of doctors about this.

Despite the fact that Postinor tablets (for abortion) have good reviews, the drug is not recommended to be used often. Doctors say that the drug deals a strong blow to the well-established hormonal background of the fairer sex. Often this leads to further problems.

Gynecologists say that the drug "Postinor" for interruption has real effectiveness only in the first three days after unprotected sexual intercourse. Later, the medicine has practically no effect on the pregnancy that has taken place. Gynecologists strongly do not recommend using the medication on their own. Before use, the patient should consult a doctor and receive individual recommendations.

What is the medicine?

The drug "Postinor" (sometimes used by women for early termination of pregnancy) has the following composition: levonorgestrel in the amount of 0.75 mg, colloidal silicon dioxide (0.5 mg), lactose monohydrate (71 mg), potato starch (0.5 mg), corn starch (23 mg), talc (3 mg), magnesium stearate (1 mg).

One package of the drug contains two tablets. The average cost of this medication is 400 rubles per pack.

The action of the drug and its effectiveness

How does the drug "Postinor" for abortion in the early stages? Instructions for use inform consumers of the following data.

Immediately after ingestion, the drug is delivered to the stomach and then to the intestines. Absorption of the drug begins immediately. The maximum concentration of the active substance in the blood of the fairer sex is detected after an hour and a half. The tool "Postinor" for abortion in the early stages has good reviews. Consumers and experts say that if you take a pill on the first day after unprotected contact, then the probability of a positive outcome will be 95 percent. When the drug is used after two days, the effectiveness is estimated at 80 percent. After three days, the medication is considered useless. However, some persons manage to interrupt

The drug has an effect on the woman's ovaries. It blocks the work of the reproductive organs. This leads to the reverse development of the follicle and the abolition of ovulation. If the release of the egg has already occurred, the medication acts on the corpus luteum, suppressing its work. In addition, the tool makes the cervical mucus more viscous. This fact prevents the penetration of spermatozoa into the uterus. If this inevitably happened, then "Postinor" begins to act on the mucous membrane of the uterus. Thus, the endometrium undergoes reverse development and is unable to accept an already fertilized cell. All these facts combined prevent further development pregnancy.

Indications for the use of the drug

In what cases is this medication used? Instructions for use indicate only one indication - the need to terminate the pregnancy. So, the remedy can be used in the case when the usual methods of contraception were ineffective. For example, missed the next birth control pill, and so on.

It is worth noting that before using it is necessary to study the instructions. Like any medication, the drug "Postinor" has limitations and contraindications.

In what cases is it necessary to refuse the use of the drug?

• Diseases of the liver and kidneys in the acute stage.
• The age of the representative of the weaker sex is up to 16 years.
• Congenital diseases of a genetic nature.
• Hypersensitivity or the possibility of an allergy to any component of the drug.
• Pregnancy, including those developing outside the uterine cavity.

The drug can be taken only after the permission of the doctor for lactation, hepatitis of various types.

How can Postinor terminate a pregnancy in the early stages?

The drug should be used strictly by induction. In this case, the effect of such a correction will be maximum. One package contains two tablets. The first of these should be taken as soon as possible after sexual contact. The sooner you do this, the greater the likelihood of a positive outcome.

The second capsule of the drug is taken 12 hours after the first. In this case, the break between them should not exceed 16 hours. That is why it is so important to correctly calculate the correction scheme with such a substance.

Doctors say that the Postinor medication is not used to terminate a pregnancy after a missed period. However, some ladies claim that they managed to terminate the pregnancy in this way. Gynecologists testify that this is just a coincidence. Normally developing pregnancy after four weeks cannot be interrupted by the use of this substance.

special instructions

If you took Postinor pills for early termination of pregnancy, then be prepared for side effects. The onset of bleeding indicates the correct operation of the drug. In most cases, it resembles normal menstruation. In this case, the next menstruation may begin within a few days after the completion of these discharges.

Often the medication causes nausea. That is why doctors do not advise eating before using the drug. It is also worth refraining from eating for several hours after taking the last pill. If vomiting occurs, then the woman needs to take an additional pill, since the effect of the correction may be incomplete.

After two weeks after the correction, it is worth visiting a gynecologist and undergoing an ultrasound examination. This will make sure that the pregnancy really does not develop.

Thanks

The site provides background information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Have you ever had a condom break during intercourse?
This probably happens to every woman at least once in her life. This is just a shock situation, because, as a rule, in such cases, pregnancy is not at all included in your plans.
What to do?
Help will come postinor. This drug is specially designed for "emergency" contraception .. site) will help you to study on this page.

What is Postinor?

Postinor refers to hormonal contraceptives that are taken orally after intercourse. Postinor can be used by those women who do not have disruptions in menstruation.

How is postinor used?

Everything is very simple and convenient. Within two days (maximum within three days from the moment of sexual intercourse), you need to drink one tablet of postinor. And twelve hours after the first pill, you should take another pill. The use of postinor is completely independent of the day of the cycle. In addition, the effect of postinor is not affected by food intake. You can take the tablet with a meal or take the tablet after a meal, or on an empty stomach. The postinor tablet should be drunk as a whole, it does not need to be crushed or cut, it can be washed down with water or any drink.

Are there any undesirable effects from taking postinor?

Yes, postinor can cause some digestive disorders in your body, such as diarrhea, vomiting or nausea. After taking postinor, the next menstruation may begin earlier or later than usual, and there may be discomfort in the mammary glands.

Can everyone take postinor?

If you suffer from diseases of the bile ducts, then you should not take postinor. It is also forbidden to use this drug for women with severe liver dysfunction. Postinor should not be used by girls during puberty, as the manufacturer warns of the lack of data on the use of postinor in such age groups of patients. If you suspect that you are already pregnant, do not take Postinor under any circumstances. This is a hormonal drug that can adversely affect the course of pregnancy and the development of the fetus. If you suffer from thrombosis or other disorders of venous circulation, then you should not take postinor. Also, do not use postinor for any bleeding from the genitals. Women with individual intolerance to the components of postinor should also not take this drug.

Can postinor be taken while breastfeeding?

It is possible, but that hour after feeding the child, take two postinor tablets at once, and in the upcoming feeding, you should express milk. Postinor during breastfeeding can only be considered an emergency method of contraception, which should be used after consulting a doctor and strictly on his recommendation.

Can Postinor be taken with other medications?

If you use drugs from the group of liver enzyme inducers, then postinor will be absorbed and excreted from the body faster.
If you are taking drugs from the groups barbiturates, tetracyclines, ampicillin, rifampicin, rifabutin, carbamazepine, phenytoin, or griseofulvin, then the effect of postinor may decrease.
Postinor should not be combined with antibiotics of the cyclosporine group, as this will harm the body.
You can safely combine postinor with vitamin and mineral herbal dietary supplements (biologically active supplements).
Do not exceed the dosage of Postinor, as this can cause a menstrual cycle to fail. Before use, you should consult with a specialist.

Reviews

Hello! I am 16 years old. Virgin. But it so happened that during sexual intercourse with a partner, the sperm got inside. After that, within 24 hours, I drank one tablet "Postinor". After a couple of hours, a brownish discharge came out. And after four days, the lower abdomen began to hurt and discharge came out. Does this mean exactly that there is no pregnancy?

Hello! I have such a situation, my period went on April 14, ended on April 19, then went again on April 28 and to this day they go, or rather, not in large quantities, I drank postinor after menstruation, I don’t remember about, somewhere on April 24 and after postinor, I have once again, the periods have not stopped until now, and in the left lower abdomen it aches a little, it doesn’t hurt much, a little, what could it be? Tell me please

Is it possible to take a break if the first tablet of pastinor has been drunk for more than 24 hours

Hello, I am 2-3 weeks pregnant, is it possible that if I drink pastero, it will cause a miscarriage?

On the 4th there was an unprotected PA, after that I took 1 tablet of Postinor On the 5th there was a second PA (without a condom) will 1 tablet help, since I took the first one on the 4th??

Hello, I drank, I’m not sure that I’m pregnant, but I drank Postinor on the 3rd day, what should happen, how will it work?

I advise you not to take out your d ... mo for general discussion.

Hello! There was an unprotected intercourse, but I managed to pull it out when I finished, the sperm flowed out slowly and not very much. The second time with a condom, I didn’t know if I finished or not, because I didn’t really feel anything. As a result, I found a small hole on the side of the head. Now we are thinking whether it is worth resorting to postinor or not? Who will advise what?

Better not!

Hello! PA happened, the condom burst inside, but the guy didn’t finish, is it worth drinking postinor?

Good night, there was a sexual intercourse, the whole thing left me with the question, from what moment can I drink tabs, if let's say this afternoon I buy them, can I do that ??

Breastfeeding a 7 month old baby. During the PA, the condom broke, I immediately went to the shower. Should I drink postinor, the day has not passed yet? I'm afraid that the child will not survive the day without a breast. Is it safe to breastfeed after taking the pill?

Hello!!! I have a problem, after taking the first pill and the second one, 21 hours have passed! How will this affect the result ???

Hello! During intercourse, the condom tears and the guy cums inside me! I took the first Postinor tablet after 17 hours and the second after 12 hours! Whether it can mean that I am pregnant????

Hello, tell me please, I have a short pregnancy, I don’t want to give birth right now, it’s like this, according to the situation, I don’t have money alone. Can I drink postinor?

I drank postinor as written in the instructions, after 5 days again not protected p.a. Do I need to drink postinor again?

Hello! Tell me please, there was an unprotected intercourse, but the guy didn’t finish there, about 10-15 minutes went to the second, but nothing happened! Now the question is, there is an opinion that after the first intercourse you need to wait about 1-1.5 hours, since spermatozoa are released from the penis and there is a chance of getting pregnant! It happened on Saturday evening, I drank 1 tablet of pastinor on Monday evening, and 2 having calculated the time incorrectly after 8 hours! Tell me what is the effect of postinor in this case? And was it worth drinking pastinor at all ?Waiting for an answer! Thanks in advance!

Hello, during intercourse, the condom broke on April 7, 2013 at about 5 o'clock. then in the evening I washed with soap. The next day, April 8, 2013, at 7 pm, she took a postinor tablet. The next one is usually after 12 hours on 04/09/13 at 7 am. what is the chance of pregnancy? because there is no way to go to the doctor. very scary. I'm only 17. As a rule, I did not plan children yet.

1-2 days after the end of menstruation, it was npa and the martyr finished in me after 40 minutes, went into the shower after another 2 hours, drank the first postinor tablet in the evening of the same day, again went into the shower after 12 hours as it should be the second. 6 days passed and there were no changes at all, neither sick nor there is no pain in the abdomen, no blood at all, everything is the same as it was. Please tell me what is the probability of getting pregnant?

No matter how sad it is to write about it, but postinor in Russia ranks second among contraceptive methods. On the first, as you know, is. And yet, many women, despite the large selection of contraceptives, use postinor to prevent unwanted pregnancy, forgetting or not knowing about the complications, and what danger the harmless 2 pills pose in the future.

Meet Postinor

Postinor is produced in a package in which there are only 2 tablets (only the number of tablets should suggest that this is not a drug for regular use). One tablet contains 750 mcg of levonorgestrel, which has an emergency contraceptive effect. Levonorgestrel has antiestrogenic and progestogenic properties.

Postinor refers to emergency or fire contraception, and should be used only in exceptional cases, and not constantly and regularly.

How does postinor work?

The contraceptive effect of the drug is in three points. Firstly, levonorgestrel prevents the release of the egg from the follicle, that is, it inhibits ovulation (this moment is especially relevant in the preovulatory and ovulatory phases). Secondly, levonorgestrel, as a progestogen, changes the structure of the uterine mucosa and causes "glandular regression" of the endometrium, which makes it impossible for a fertilized egg to penetrate into the uterine wall (violation of implantation). This mechanism is comparable to, that is, conception has already occurred, but the uterus expels the egg. And thirdly, levonorgestrel causes changes in the mucus in the cervical canal, making it viscous and thick. Such mucus plays the role of a barrier and makes it difficult for sperm to enter the uterine cavity.

From the described mechanisms of action of postinor, it becomes clear that the effectiveness of the drug is directly proportional to the time it is taken after unprotected sex. After using postinor 24 hours or less after sexual intercourse, it will protect against unwanted pregnancy in 95% of cases, when taking pills after 25-48 hours, the effectiveness is 85%, and if postinor was taken in the interval from 49 to 72 hours, its reliability decreases up to 58%.

Rules for accepting a postinor

Postinor can be taken on any day of the menstrual cycle. If a woman has an irregular menstrual cycle, the absence of pregnancy should be confirmed. The first tablet from the blister should be taken no later than 72 hours after intercourse. The second dose should be taken exactly 12 hours later (an interval of 4 hours is allowed, that is, no more than 16 hours later).

If a woman vomits within three hours after taking a postinor tablet (regardless of the first or second one), an additional tablet should be taken. Menstrual-like bleeding (withdrawal bleeding) can occur a few days after taking the drug (on average after 3 to 7 days) and about a month later (at the time of the expected period).

Postinor is not a means for regular contraception, if a woman has an active sex life, she should consult a doctor and choose the best method of contraception. It is believed that you can not use the drug more than once a month, and preferably no more than 4 times a year. In fact, it is better not to resort to postinor at all, but to use it only in an exceptional situation.

When is postinor justified?

Life is an unpredictable thing and there are situations when it is necessary to prevent pregnancy:

• rape;
• the condom broke;
• unprotected intercourse for various reasons;
• expulsion of the intrauterine device or shift of the vaginal diaphragm;
• missed taking a pill from a series of combined oral contraceptives.

Consequences after using postinor

Since the drug contains an "elephant" dose of the hormone, its use can adversely affect a woman's health. Firstly, there is a high probability of uterine bleeding, which can only be stopped surgically (that is, by curettage of the uterus). Secondly, taking postinor, especially more than once in a lifetime, hits the ovaries, which leads to menstrual irregularities, hormonal imbalance and anovulation. All of these effects are a direct path to infertility. Thirdly, a large dose of levonorgestrel cannot but cause side effects:

• nausea and vomiting, diarrhea;
• headache, dizziness;
• mood swings (emotional lability, panic fears);
• delay of menstruation;
• allergic reactions;
• pain in the lower abdomen, fatigue;
• pain and engorgement of the mammary glands.

Postinor is a popular drug for preventing unwanted pregnancy. It is a synthetic gestagen with a contraceptive effect, pronounced gestagenic and antiestrogenic properties. Efficacy: With the help of pills, pregnancy can be prevented in about 85% of cases. The more time elapsed between sexual intercourse and taking the drug, the lower its effectiveness (95% during the first 24 hours, 85% from 24 to 48 hours and 58% from 48 to 72 hours).

Indications for use

Contraceptive pills for emergency prevention against unwanted pregnancy are used for:

• breaking a condom during intercourse;
• slipping off a condom during intercourse;
• a single missed birth control pill;
• spontaneous prolapse of the intrauterine device;
• unprotected intercourse during expected ovulation;
• failed interrupted act;
• unprotected intercourse;
• rape.

Contraindications for use

Postinor has a number of contraindications for use, these include:

• an allergic reaction to the components contained in Postinor;
• age less than 18 years (also not recommended for women over 40 years of age due to the risk of thrombosis);
• liver failure;
• pregnancy that has already been established;
• allergic reaction (intolerance) to lactose;
• Crohn's disease;
• cholelithiasis;
• uterine bleeding;
• varicose veins of the lower extremities;
• lactation.

What is dangerous Postinor

The same pills act on each woman individually. That is why, when describing side effects, all these symptoms do not mean that this occurs in every woman when taking the drug. Side effects include:

• Violation of the digestive tract (nausea, vomiting, indigestion, stool disorders).
• Pain in the region of the breast.
• Failure of the menstrual cycle (manifested as a delay in menstruation or, on the contrary, an earlier onset of menstruation).
• The appearance of bleeding after taking the pills, which is not associated with menstrual bleeding.
• Ectopic pregnancy.
• Violation of the central nervous system, manifested in the form of increased fatigue, migraine, dizziness.

In general, all side effects go away on their own within two to three days, but if you do not feel better after taking the pills and more than four or five days have passed, then you need to urgently see a doctor.

Description of the drug, instructions for use

The onset of pregnancy depends on the menstrual cycle, or rather on the immediate day of the menstrual cycle. In a healthy woman of reproductive age, ovulation occurs within 12 hours. Let's remember what ovulation is. Ovulation means when a mature egg leaves the ovary, where it begins to move in the fallopian tube towards the sperm, where they meet. If such a meeting occurs, then an embryo begins to form. For the onset of pregnancy, one unprotected sex is sufficient 3 days before ovulation. And after ovulation within one day. After a successful meeting and formation of the embryo, it takes 3-5 days for its implantation.

In order to decide to take emergency hormonal drugs, it is necessary to assess the exact possibility of pregnancy. If you know the exact time of ovulation, then 2-3 days after ovulation, you cannot get pregnant. At present, the onset of ovulation is quite simple to know. There are specific tests.

Thus, the use of Postinor is necessary during the first day after unprotected intercourse and no later than 3 days after unprotected intercourse.

It must be remembered that the drug is absolutely not effective if implantation has already occurred. Postinor does not provoke a miscarriage.

Postinor itself is two white tablets, shaped like a disc and engraved with INOR

The drug is able to prevent unwanted pregnancy by 85%, but the more time passes after intercourse, the less effective it is. For example:

• 90% - taking the drug in the first 24 hours after intercourse;
• 80% - taking the drug from 24 hours to 48 hours after sexual intercourse;
• 50% - taking the drug from 48 hours to 72 hours after sexual intercourse.

Tablets are used inside. The first tablet is drunk no later than 72 hours after unprotected intercourse, and the second tablet is taken exactly 12 hours after taking the first, no later than 16 hours.

If no more than 3 hours have passed after taking the pill and vomiting has occurred, then you must urgently take another Postinor tablet.

Postinor is used at any time of the day and on any day of the menstrual cycle.

Repeated use of Postinor is strongly not recommended during one menstrual cycle.

Doctors recommend using all emergency contraceptive drugs no more than once every six months. More frequent use can lead to the development of pathologies from the reproductive system. The result may be infertility. As practice shows, a woman who does not use emergency protection does not violate the natural process of the menstrual cycle and has no further problems with conception.

Conditions of sale, storage and expiration dates

The drug must be stored at room temperature not lower than 15 degrees and not higher than 25 degrees, out of the reach of children.

The shelf life of the drug is 5 years.

The drug is dispensed by prescription.

How to understand if Postinor worked

If the menstrual flow came on time: the duration, the volume of discharge did not change, then the drug definitely worked. But there are times when you need to urgently consult a doctor, for example, you observe:

• copious discharge;
• discharge is very scanty;
• delay in menstrual flow for more than 6 days;
• menstrual flow is accompanied by severe pain in the lower abdomen (the pain is aching in nature or cramping);
• the appearance of a sharp pain in the lower abdomen.

What does the delay after taking the drug mean?

Initially, it is necessary to exclude the onset of pregnancy. To do this, you can do a pregnancy test at home. If the test is positive, then you are pregnant. And if negative, then there is no pregnancy. In this case, it is necessary to exclude an ectopic pregnancy. To do this, you must either consult a gynecologist or do an ultrasound examination of the pelvic organs.

If pregnancy is completely excluded, then a delay after taking Postinor (more than 10 days) can be justified:

• inflammatory processes of the pelvic organs (endometritis, adnexitis, vaginitis, colpitis);
• hormonal imbalance;
• the presence (more precisely, the influence of Postinor) of endocrine disorders;
• pathology of the urinary system.

When does menstruation start after taking the drug

Usually, the onset of menstruation after taking the drug may not coincide with the expected date. The first discharge can be of a meager nature, which disappear 2-3 days after the onset and can be repeated 2 times within one month. This indicates the correct operation of the drug.

But mostly menstrual bleeding comes either on time or 2-5 days before the expected date. And also with a delay of up to 5-7 days before the expected date.

Is it worth taking Postinor if NPC occurred during menstruation

The menstrual cycle is considered one of the complex physiological processes. If we consider the full phase of the menstrual cycle, then the most favorable conditions for conception is the middle of the cycle.

That is why it is believed that the likelihood of getting pregnant during menstrual bleeding is impossible. But, as practice shows, there is still a chance of pregnancy during menstruation.

The best conditions for conception is the middle of the cycle, where female hormones begin to stimulate the production of follicles, eggs. In the remaining phases, the conditions for the onset of conception are not favorable, but it is impossible to say unequivocally that pregnancy will not occur in other phases.

That is why, it is only your choice whether or not to drink Postinor after unprotected intercourse during the menstrual cycle.

Overdose

As practice shows, cases of overdose are not described. Perhaps only side effects in the form of nausea, vomiting, bleeding.

Interaction

According to the results of the study of the drug, it was revealed that:

• Metabolism is accelerated when used simultaneously with liver enzyme inducers.
• Metabolism slows down when used simultaneously with drugs such as: phenytoin, carbamazepine, St. John's wort, ritonavir, rifabutin, griseofulvin.

Bleeding after taking the drug, how to stop them correctly

Postinor is a fairly strong hormonal drug. Many women are interested in whether there should be spotting after taking the drug.

As a result of the impact of Postinor on the hormonal background of a woman, some rejection of the epithelium occurs. That is why spotting can be observed and this is considered the norm.

Such secretions are usually brown in color, rather scarce in volume. They occur after taking the pills on the 3rd, 6th day.

It is worth remembering that if spotting began a week after taking the drug, then this indicates the development of a pathological process. You need to see a doctor urgently.

Normally, spotting can go on for 3-7 days, but in some cases, these discharges can go on for two weeks. In this case, you need to consult a specialist. You should also pay special attention to an urgent visit to the doctor if:

• there was pain in the lower abdomen;
• discharge has an admixture of pus;
• the appearance of foamy secretions;
• an increase in body temperature that is not associated with a cold.

How to stop bleeding? This issue is of particular interest to women. In such cases, self-treatment can lead to the development of pathologies and complications. If spotting is profuse in nature for a duration of more than 8-10 days, then it is urgent to consult a specialist. The doctor is already prescribing therapy.

The nature of the discharge after taking Postinor

Any bleeding can cause great harm to the life and health of a woman. Particular attention should be paid if a woman began to feel:

• weakness;
• copious discharge that does not subside;
• dizziness;
• nausea;
• shortness of breath;
• the duration of the discharge is more than 14 days.

special instructions

Use during pregnancy and lactation: Postinor should not be used during pregnancy. This drug does not terminate a pregnancy.

During breastfeeding, the use of Postinor is possible. Since it has been proven that levonorgestrel, in general, does not pass into breast milk. It is recommended to use both the first and the second tablet immediately after breastfeeding. And skip breastfeeding once after taking the pills. This will significantly reduce the impact of pills on the development of the child.

Is it possible to get pregnant after taking Postinor

Improper use of Postinor tablets can lead to pregnancy. You must strictly follow the instructions. And remember, the sooner you start taking the drug, the more likely you are to protect yourself from an unwanted pregnancy.

Postinor and its analogues

Escapelle. Most often, doctors prescribe Escapel as a replacement for Postinor. Also, the main substance, as in Postinor, is levonorgestrel. But it is considered stronger. So its concentration is increased several times. The drug is available in one tablet per pack. It is used once, within three days after unprotected intercourse. All side effects are pretty similar. These include:

• weakness;
• nausea;
• vomit;
• headache;
• pain in the mammary glands.

Jenale. The composition of the main component includes mifepristone. Applied once. It is recommended to apply either 2 hours before meals or after. It is recommended to use the drug no later than 72 hours after unprotected intercourse. Side effects are basically the same, these include:

• nausea;
• vomit;
• stool disorder;
• migraine;
• dizziness;
• failure of the menstrual cycle;
• intermenstrual bleeding.

Ginepriston. In the composition of this drug, the main component is mifepristone. It is applied once within 72 hours or 2 hours before or after meals. But there are a few other side effects, these include:

• hives;
• pathological discharge from the vagina;
• pain in the lower abdomen;
• discomfort in the external genital area;
• weakness.

Postinor and alcohol.

If you study the instructions for using Postinor, then it does not describe the effect of alcohol while taking the pills. Since Postinor itself is a rather complex drug and has many side effects. That is why, in order to avoid unwanted complications, it is better to refuse alcohol.

1 tablet contains 750 mcg , as well as anhydrous colloidal silicon dioxide, magnesium stearate, potato and corn starch, talc, lactose monohydrate.

Release form

Tablets packaged in blisters of 2 pcs. The package contains 1 blister.

Contraceptive pills Postinor are flat, approximately 6 mm in diameter, with a chamfer, almost white, on one side they are engraved with the inscription "INOR".

pharmachologic effect

The drug helps to prevent pregnancy, causes effects in the body similar to the action of hormones of the corpus luteum of the ovaries, and also suppresses the effects caused by .

Pharmacodynamics and pharmacokinetics

What is Postinor?

Postinor is a remedy with a pronounced antiestrogen and progestogenic activity. These properties of the drug make it difficult to conceive at an early stage and help prevent pregnancy.

Pharmacodynamics

How Postinor works is not exactly known. Contained in tablets levonorgestrel prevents ovulation and fertilization of the egg if UPC (unprotected sexual intercourse) happened before ovulation (when fertilization is most likely).

Levonorgestrel also causes changes in the endometrium, which make it difficult for a fertilized egg to enter the mucous layer of the uterine cavity. In cases where the attachment of the fetal egg has already begun, the drug does not give the expected effect.

Wikipedia states that the mechanism of action levonorgestrel is most successful when the size of the dominant follicle is 17 mm. Best of all, the drug suppresses ovulation no later than three days before it.

The effectiveness of tablets

The probability of pregnancy after the use of Postinor tablets is 15-42%. The action after taking the better, the less time has passed after NPC.

If the drug was taken within 24 hours, its effectiveness is 95%, in the next 24 hours it decreases to 85%, on the third day - up to 58%. It makes no sense to take the drug later than 72 hours later.

Is Postinor harmful?

Pharmacokinetics

Absorption in the alimentary canal when ingested is rapid and complete. In the body, the drug binds to SHBG and albumin: approximately 65% ​​of the dose taken is associated with SHBG, only 1.5% is in the free form.

96 minutes after taking the tablet, the plasma concentration levonorgestrel reaches 14.1 ng/ml. Then there is a 2-stage decrease in Cmax.

The drug is well distributed in tissues and organs.

Its biotransformation is carried out in the liver. The resulting metabolic products (conjugated glucuronates) are pharmacologically inactive.

Levonorgestrel It is excreted from the body exclusively in the form of metabolic products. About half of the dose taken is excreted in the urine, the rest - in the faeces. The value of T1 / 2 varies from 9 to 14.5 hours.

With milk, about 0.1% of the dose enters the body of an infant when a nursing woman takes Postinor.

Indications for use

“Urgent” contraception in case of failure of the chosen method of contraception or after CPD.

Contraindications

A contraindication to the use of the drug is intolerance levonorgestrel or any of the auxiliary ingredients contained therein.

The drug is used in pediatric practice. Data regarding its use in girls under 16 years of age are limited, therefore, in adolescence, Postinor is not recommended to be taken without medical supervision.

Side effects of Postinor: why is the drug dangerous?

In the annotation to the drug, the manufacturer reports that the most common reaction to the use of levonorgestrel is nausea .

In addition, the following side effects of Postinor were recorded during the studies:

• dizziness;
• headache;
• and vomit ;
• nausea;
• not related to the menstrual cycle ;
• failure of the menstrual cycle (namely, a delay in menstruation after taking the pill for more than a week);
• increased fatigue.

Post-marketing observations have shown that sometimes (quite rarely) the use of the drug may be accompanied by: hypersensitivity reactions ( , the appearance of rashes on the skin, skin itching), , pain in the pelvis and / or in the abdomen, swelling of the face.

What is harmful Postinor?

Reviews of side effects allow us to conclude that the most unpleasant, according to women, phenomena after taking Postinor:

• bleeding (in some reviews it is mentioned that, not knowing how to stop the bleeding after Postinor, the woman was forced to seek medical help);
• severe hormonal imbalance and severe cycle disorders (many cases have been described when, after taking Postinor, there are no periods for several cycles; it takes up to a year for someone to restore the regularity of menstruation).

This list can include the appearance of "male" signs, metabolic disorders and acne .

Sometimes the consequences of taking Postinor tablets manifest themselves in the form of miscarriage of subsequent pregnancies and infertility.

To minimize harm to the body, the drug should be used no more than 3-4 times a year.

Tablets Postinor: instructions for use

How to take Postinor?

The instructions for Postinor indicate that the contraceptive effect is provided by taking two tablets (provided that the first tablet is drunk in the first 3 days after the NPC). Between doses 1 and 2 doses withstand a twelve-hour interval.

If within 3 hours after the drug was drunk (regardless of whether 1 or 2 doses), you should immediately take another 750 mcg levonorgestrel (3rd tablet).

The tool can be used in any phase of the menstrual cycle. A prerequisite is the absence of a woman's delay in menstruation.

After taking the pills before the start of the next menstruation, it is recommended to use funds barrier contraception (cervical cap or condoms).

Taking the drug is not a contraindication for the continued use of hormonal contraceptives for regular use.

How to understand that the drug has worked?

The tablet begins to act immediately after dissolution and absorption in the intestinal tract.

The evidence that the drug "worked" is menstruation.

Bleeding after consumption excludes pregnancy in about 95-85% of cases if it begins 3-6 days after taking the pill.

What can the delay after Postinor indicate?

If there is no bleeding after taking the drug, or if the bleeding begins later than the indicated dates, the woman is recommended to do and undergo an examination by a gynecologist to exclude pregnancy.

It is worth consulting a doctor not only with a delay in menstruation, but also if, after taking Postinor, the consequences are expressed in the form of unusually strong bleeding for a woman. The causes of such bleeding may be an excess of the recommended dose and the negative impact levonorgestrel on the uterine endometrium .

Sometimes women note that they have brown discharge after taking it. The phenomenon is considered the norm if the discharge appears within a few days, thus completing the menstruation artificially induced by the pills. However, for some women, spotting can last up to a month.

Most likely, this is an individual reaction to severe stress for the reproductive system, but only a doctor can accurately diagnose the cause of the discharge.

Cause for concern are menstrual bleeding lasting more than 14 days, the absence of a full period, the appearance of clots or heavy brown discharge, pain.

When should my period start after taking the pills?

It is impossible to say exactly when menstruation will begin after the use of Postinor. The tablets contain a large amount levonorgestrel Therefore, even a single use of the drug does not pass without a trace for the body.

In most cases, after taking the remedy, the menstrual cycle remains the same. Sometimes bleeding may start earlier or later. Normally, the delay should not be more than 5-7 days. Otherwise, pregnancy should be excluded.

After taking levonorgestrel a woman is advised to visit a doctor who will help her choose the most suitable method of regular contraception.

Is it worth taking Postinor if NPK occurred during menstruation?

Women with irregular cycles are more likely to get pregnant even during their menstrual bleeding. The appropriateness of the use of "urgent" contraceptives, if the NPC occurred during menstruation, can be determined by the doctor.

How often can I take Postinor?

To the question “How often can I take emergency contraceptive pills?” doctors answer that Postinor-type drugs are not intended for systematic use. They are used only in emergency situations and no more than 3-4 times a year.

Overdose

Clinical picture of overdose hormonal means emergency contraception not described. Most likely, the first signs of poisoning will be nausea and breakthrough bleeding.

Postinor does not have a specific antidote.

Interaction

In combination with liver enzyme inducers, metabolism is activated levonorgestrel .

The effectiveness of drugs that contain levonorgestrel , may decrease with simultaneous use with:

• barbiturates ;
• preparations of St. John's wort (Hypericum perforatum);
• rafibutin ;
• ritonavir ;
• phenytoin ;

Women taking these drugs should consult a doctor before taking Postinor.

Levonorgestrel-containing drugs can lead to increased toxicity , which is associated with the possible suppression of its metabolism.

Terms of sale

On prescription.

Storage conditions

Tablets should be stored at 15-25°C.

Best before date

special instructions

Means of "urgent" contraception are intended for occasional use and do not replace the regular method of contraception.

“Emergency” contraception does not always prevent pregnancy. If there is any doubt as to the timing of CPP, or if an unprotected intercourse has taken place more than 72 hours during the same cycle, the possibility that a fertilized egg has already implanted in the uterine wall cannot be ruled out.

In this regard, the use of tablets at the next sexual contact may be ineffective. If the cycle is delayed by more than 5 days, if atypical bleeding develops on the day of the expected menstruation, as well as if there are other reasons to suspect the occurrence of pregnancy, the fact of pregnancy should be excluded.

After taking levonorgestrel there is a risk of developing ectopic pregnancy . The absolute probability of this is low, since the drug interferes with ovulation and fertilization.

Ectopic pregnancy may persist despite the occurrence of uterine bleeding.

most likely in women who noted fainting or severe pain in the abdomen, as well as in the presence of a history of surgery on the fallopian tubes, , or PID .

Based on this, patients at risk are not recommended to take Postinor tablets.

Taking pills can slightly change the nature of bleeding, but in most cases the next menstruation begins a maximum of a week after the usual date.

With a delay in menstrual bleeding for more than 5 days, it is necessary to exclude the fact of pregnancy.

The drug should not be used in women with serious liver pathologies. The effectiveness of tablets can be negatively affected by severe malabsorption (eg, granulomatous enteritis ).

For women suffering from similar diseases, before carrying out emergency contraception it is recommended to consult a doctor.

Postinor tablets contain lactose, which should be warned in patients with lactase deficiency and malabsorption of glucose and galactose .

The drug is ineffective as regular contraceptives and is not an alternative. It should also be remembered that this tool does not replace the necessary precautions related to protection against STD .

If a woman seeks repeated use of Postinor, the doctor should recommend that she use long-term methods of contraception.

Impact Studies levonorgestrel on the ability to drive a vehicle or work with mechanisms were not carried out, but one should forget about the possibility of dizziness. levonorgestrel. Only in the first case, its concentration is 1.5 mg / tab., And in the second - 0.75 mg / tab.. That is Escapelle in the case of NPC, it should be taken once, and Postinor - in 2 doses with an interval of 12 hours.

Which is better - Genale or Postinor?

Active substance Jenale - synthetic antiprogestin . The substance is a derivative norethisterone and is used to terminate early pregnancy. Its content in each tablet is 10 mg.

Mifepristone is non-hormonal agent , which reversibly and briefly blocks only peripheral PR (receptors progesterone ). Depending on the phase of the menstrual cycle, the drug prevents the release of luteotropin , delays or blocks ovulation and causes disturbances in the transformation of the endometrium, which, in turn, makes it difficult for the implantation of the egg.

WHO data indicate that the use of low doses mifepristone more effective and safer than emergency contraception using levonorgestrel .

In addition, it has been experimentally proven that the contraceptive effect mifepristone does not decrease with an increase in the interval between NPK and reception Jenale up to 120 hours. This is also a significant advantage of the latter over Postinor.

If necessary "urgent" contraception it is enough to take 1 tablet during the first 72 hours Jenale . The drug is used 2 hours before meals.

Which is better - Postinor or Ginepriston?

active substance Ginepristone is also mifepristone at a concentration of 10 mg / tab .. Thus, the drug has the same advantages over Postinor as Jenale .

The tool is highly effective, characterized by the absence of pronounced side effects and can be used for episodic contraception in women with an irregular sexual life.

In addition, the drug is more affordable than Postinor. Its price in Russian pharmacies is about 100-120 rubles lower than the price of Postinor.

Postinor and alcohol

Is it possible to combine Postinor tablets with alcohol? There are no recommendations in the manufacturer's instructions for this.

However, it should be remembered that alcohol is not compatible with the vast majority of pharmaceutical products.

The use of alcoholic beverages in combination with Postinor can cause a sharp expansion, and then an equally sharp vasoconstriction, which in turn will complicate the woman's condition when the drug provokes rejection of the uterine mucosa.

In addition, alcohol increases the level of liver enzymes, thereby speeding up the metabolism. Since biotransformation levonorgestrel carried out in the liver, the contraceptive effect of Postinor while taking alcohol can be very doubtful.