Paracetamol for joint inflammation. Paracetamol for joint pain: methods of use

Studying diseases musculoskeletal systems, doctors have found Paracetamol effective for joint pain. For best result Along with it, they also take other medications prescribed by the attending physician. The medicine has antipyretic and anti-inflammatory effects. It is allowed to be consumed by adults and children, taking into account the correctly calculated dosage for joint diseases.

Composition and release form

• The main element is paracetamol.
• Additional elements:
  • povidone;
  • croscarmellose sodium;
  • stearic acid;
  • potato starch.

Paracetamol has the following release forms:

• syrup;
• pills;
• capsules;
• suppositories.

Indications for use of the drug

Paracetamol is used when experiencing mild or moderate pain. These include:

The drug is effective for toothache.

• head;
• dental
• joint pain;
• pain from injuries;
• migraine;
• neuralgia;
• menstrual;
• muscle pain resulting from exercise or for no apparent reason;
• an increase in temperature due to a cold or other infectious and inflammatory processes.

The use of Paracetamol for the treatment of joint pain

Paracetamol is used for lung treatment or moderate malaise with rheumatoid arthritis. It effectively relieves pain, improving the patient's condition.

The drug is taken orally or rectally. You must follow the dosage indicated in the instructions:

• For adults weighing over 60 kg, it is recommended to take the medicine before meals 3-4 times a day within a period of 4-6 hours.
• The product in tablet form is intended for adolescents over 12 years of age. The dosage is no more than 2 tablets. per day.
• For children 6-12 years old, the period of use will be 4 times a day with an interval of at least 6 hours.
• At the age of 1-5 years - 120-250 ml in the form of syrup.
• From birth to one year - 60-120 ml of suspension or rectal suppositories, the dosage of which is prescribed by the pediatrician.

Side effects and contraindications

If you take the drug longer than necessary, you may experience abdominal pain.

• nausea;
• stomach ache;
• impaired liver and kidney function;
• skin rash;
• anemia.

Although Paracetamol is considered a gentle pharmaceutical, even its use has limitations:

• The capsules are contraindicated for people suffering from alcoholism.
• You should take tablets for arthritis for no more than 4 days.
• It is recommended to first familiarize yourself with the substances that make up Paracetamol to avoid an allergic reaction.
• Elderly people should not overuse the medicine.
• It is important to use the drug with caution in patients suffering from renal failure or liver disease.

Using Paracetamol will help reduce joint pain. It has a positive effect on the body, stopping inflammatory processes and helping to restore health. You can buy it at any pharmacy without a prescription from a doctor. The choice is large, since the drug is sold in various forms, among which you can choose the most convenient one. The use of the medicine does not lead to serious consequences.

It has been established that paracetamol is a weak inhibitor of prostaglandin biosynthesis, and its blocking effect on the synthesis of prostaglandins - mediators of pain and temperature reaction - occurs to a greater extent in the central nervous system than in the periphery. This explains the presence of a pronounced analgesic and antipyretic effect of paracetamol and a very weak anti-inflammatory effect. Paracetamol practically does not bind to plasma proteins, easily penetrates the blood-brain barrier, and is almost evenly distributed in the brain. The drug begins to have a rapid antipyretic and analgesic effect after about 20-30 minutes and continues to act for 4 hours. The period of complete elimination of the drug is on average 4.5 hours.

The drug is primarily excreted by the kidneys (98%), the main part of the administered dose is biotransformed in the liver. Due to the fact that paracetamol has virtually no effect on the gastric mucosa, i.e., it does not cause an ulcerogenic effect. This also explains the absence of bronchospasm when using paracetamol, even in people suffering from bronchial asthma. The drug does not affect, unlike aspirin, the hematopoietic system and the blood coagulation system.

These advantages, as well as the wide range of therapeutic effects of paracetamol, have now allowed it to take its rightful place among other non-narcotic analgesics. Preparations containing paracetamol are used for the following indications:

1. Pain syndrome of low and medium intensity of various origins (headache, toothache, neuralgia, myalgia, pain from injuries, burns).
2. Febrile fever in infectious and inflammatory diseases. It is best used as an antipyretic in pediatric practice.

Sometimes aniline derivatives (phenacetin, for example) are combined in one tablet with other non-narcotic analgesics, thus obtaining combined agents. Most often, phenacetin is combined with AA and codeine. The following are known combination drugs: asphen, sedalgin, citramon, pirkofen, panadeine, solpadeine.

Side effects are few and are more due to the administration of phenacetin than paracetamol. Reports of serious adverse reactions to paracetamol are rare and are usually associated with either an overdose of the drug (more than 4.0 per day) or with prolonged use (more than 4 days). Only a few cases of thrombocytopenia and hemolytic anemia associated with taking the drug have been described. The most frequently reported development of methemoglobinemia with the use of phenacetin, as well as the hepatotoxic effect.

As a rule, modern non-narcotic analgesics primarily have a pronounced anti-inflammatory effect, which is why they are most often called NSAIDs.

These are chemical compounds of various groups, mainly salts of various acids:

• acetic acid derivatives: indomethacin, sulindac, ibufenac, sofenac, pranoprofen;
• propionic acid derivatives: ibuprofen, naproxen, ketoprofen, surgam, etc.;
• anthranilic acid derivatives: flufenamic acid, mephenanoic acid, voltaren;
• nicotinic acid derivatives: niflumic acid, clonixin;
• oxicams (enolic acids): piroxicam, isoxicam, sudoxicam.

Indomethacin(Indometacinum; capsules and dragees 0.025 each; suppositories - 0.05) is a non-steroidal anti-inflammatory drug (NSAID), which is a derivative of indoleacetic acid (indole). It has anti-inflammatory, analgesic and antipyretic activity. This is one of the most powerful NSAIDs and is the standard NSAID. NSAIDs, unlike salicylates, cause reversible inhibition of prostaglandin synthetase (COX).

Its anti-inflammatory effect is used for exudative forms of inflammation, rheumatism, and disseminated (systemic) diseases. connective tissue(SLE, scleroderma, periarthritis nodosa, dermatomyositis). The drug is most effective for the inflammatory process accompanied by degenerative changes in the joints of the spine, deforming osteoarthritis, and psoriatic arthropathy. Used for chronic glomerulonephritis. Very effective in acute attacks of gout, the analgesic effect lasts for 2 hours.

In premature babies, it is used (1-2 times) to close the functioning ductus arteriosus.

It is toxic, therefore, in 25-50% of cases, pronounced side effects occur (cerebral: headache, dizziness, ringing in the ears, confusion, blurred visual perceptions, depression; from the gastrointestinal tract: ulcers, nausea, vomiting, dyspepsia; skin: rashes; blood: dyscrasia; sodium ion retention; hepatotoxic). Children under 14 years old are not recommended.

The next NSAID is IBUPROFEN(Ibuprofenum; 0.2 in the table) - synthesized in 1976 in England. Ibuprofen is a derivative of phenylpropionic acid. In terms of anti-inflammatory activity, analgesic and antipyretic effect, it is close to salicylates and even more active. Well absorbed from the gastrointestinal tract. Better tolerated by patients than AA. When taken orally, the frequency of adverse reactions is lower. However, it also irritates the gastrointestinal tract (to the point of ulceration). In addition, if you are allergic to penicillin, patients will also be sensitive to brufen (ibuprofen), especially patients with SLE.

92-99% bound to plasma proteins. It slowly penetrates into the joint cavity, but lingers in the synovial tissue, creating higher concentrations in it than in the blood plasma and slowly disappearing from it after withdrawal. It is quickly eliminated from the body (T ½ = 2-2.5 hours), and therefore frequent administration of the drug is necessary (3-4 times a day - the first dose before meals, and the rest after meals to prolong the effect).

Indicated for: treatment of patients with RA, deforming osteoarthritis, ankylosing spondylitis, and rheumatism. It has the greatest effect in the initial stage of the disease. In addition, ibuprofen is used as a strong antipyretic.

A drug close to Brufen - NAPROXEN(naprosyn; table 0.25) is a derivative of naphthylpropionic acid. Rapidly absorbed from the gastrointestinal tract, maximum concentration in the blood is after 2 hours. 97-98% bound to plasma proteins. Penetrates well into tissues and synovial fluid. Has a good analgesic effect. The anti-inflammatory effect is approximately the same as butadione (even higher). The antipyretic effect is higher than that of aspirin and butadione. Is different long-term action, so it is prescribed only 2 times a day. Well tolerated by patients.

Apply it:

1. as an antipyretic; in this regard, it is more effective than aspirin;
2. as an anti-inflammatory and analgesic agent for RA, chronic rheumatic diseases, and myositis.

Adverse reactions are rare and occur in the form of dyspeptic symptoms (heartburn, abdominal pain), headache, sweating, and allergic reactions.

The next modern NSAID is SURGAM or thioprofenic acid (tables 0, 1 and 0, 3) - a derivative of propionic acid. Has analgesic and anti-inflammatory effects. The antipyretic effect of the drug was also noted. The indications and side effects are the same.

DICLOFENAC SODIUM(voltaren, ortofen) is a derivative of phenylacetic acid. This is one of the most active anti-inflammatory drugs today; its potency is approximately equal to indomethacin. In addition, it has a pronounced analgesic and antipyretic effect. In terms of anti-inflammatory and analgesic effect, it is more active than aspirin, butadione, and ibuprofen.

It is well absorbed from the gastrointestinal tract; when taken orally, the maximum concentration in the blood occurs after 2-4 hours. It is intensively subjected to presystemic elimination, and only 60% of the dose taken enters the circulatory system. 99% bound to plasma proteins. Quickly penetrates into the synovial fluid.

It has low toxicity, but a significant breadth of therapeutic action. It is well tolerated, sometimes only causing dyspeptic and allergic reactions.

Indicated for inflammation of any location and etiology, but it is mainly used for rheumatism, RA and other connective tissue diseases (ankylosing spondylitis).

PIROXICAM(isoxicam, sudoxicam) is a new non-steroidal anti-inflammatory drug, different from other NSAIDs, a derivative of oxicam.

Satisfactorily absorbed from the gastrointestinal tract. The maximum concentration in the blood occurs after 2-3 hours. When taken orally, it is well absorbed, its half-life is about 38-45 hours (this is for short-term use, and for long-term use - up to 70 hours), so it can be used once a day.

SIDE EFFECTS: dyspepsia, occasionally hemorrhages.

Piroxicam inhibits the formation of interleukin-1, which stimulates the proliferation of synovial cells and their production of neutral proteolytic enzymes (collagenase, elastase) and prostaglandin E. IL-1 activates the proliferation of T-lymphocytes, fibroblasts and synovial cells.

In blood plasma it is 99% bound to proteins. In patients with rheumatoid arthritis, it penetrates well into the synovial fluid. Doses of 10 to 20 mg (1 or 2 tablets) cause analgesic (30 minutes after administration) and antipyretic effects, and higher doses (20-40 mg) cause anti-inflammatory effects (by the end of 1 week of continuous use). Unlike aspirin, it is less irritating to the gastrointestinal tract.

The drug is used for RA, ankylosing spondylitis, osteoarthritis and exacerbation of gout.

All of the above agents, with the exception of salicylates, have a more pronounced anti-inflammatory effect than other agents.

They suppress exudative inflammation and the accompanying pain syndrome well and have a significantly less active effect on the alterative and proliferative phases.

These drugs are better tolerated by patients than aspirin and salicylates, indomethacin, butadione. This is why these drugs began to be mainly used as anti-inflammatory drugs. Hence they received the name - NSAIDs (non-steroidal anti-inflammatory drugs). However, in addition to these new NSAIDs, non-steroidal PVS also largely include old drugs - non-narcotic analgesics.

All new NSAIDs are less toxic than salicylates and indomethacin.

NSAIDs not only do not have an inhibitory effect on destructive processes in cartilage and bone tissue, but in some cases they can even provoke them. They disrupt the ability of chondrocytes to synthesize protease inhibitors (collagenase, elastase) and thereby increase damage to cartilage and bones. By inhibiting the synthesis of prostaglandins, NSAIDs inhibit the synthesis of glycoproteins, glycosaminoglycans, collagen and other proteins necessary for cartilage regeneration. Fortunately, deterioration is observed only in some patients; in most, limiting inflammation can prevent further development pathological process.

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The choice of drug depends on the severity of the disease, the presence of other concomitant diseases, risk of development side effects and the need to take other medications. depends on the successful actions of the doctor, and also, to a large extent, on the patient himself. Regular taking of medications, timely feedback from the doctor, and strict adherence to recommendations can greatly improve the patient’s quality of life.

The main groups of drugs used in the treatment of arthritis: painkillers and non-steroidal anti-inflammatory drugs, glucocorticosteroids, basic therapy drugs, chondroprotectors, immunomodulatory drugs, vitamins and minerals.

Painkillers (analgesics)

Analgesics relieve pain but not inflammation, unlike nonsteroidal anti-inflammatory drugs (NSAIDs). They are most often prescribed to treat osteoarthritis and some other painful but non-inflammatory forms of arthritis. Such medications may contain aspirin, codeine, or a combination of these. With proper use of these drugs, side effects rarely occur. In any case, you should not exceed the dose recommended by your doctor and use the drug for a long time without consulting a doctor.

Nonsteroidal anti-inflammatory drugs

NSAIDs are used to relieve inflammation and swelling, reduce pain and joint stiffness. This is a group of drugs widely used for the treatment of arthritis; nonsteroidal drugs include more than 40 medicinal names. They are effective in relieving the symptoms of arthritis, but cannot slow down the process of joint destruction.

NSAIDs block the release of prostaglandins and hormone-like substances, which cause inflammation and pain. If non-steroidal anti-inflammatory drug therapy is effective, within a week patients feel an increase in joint mobility and a decrease in pain. The most popular NSAIDs are Ketorolac (Ketanov), Diclofenac (Voltaren, Ortofen, Naklofen), Indomethacin, Analgin, Piroxicam, Naproxen, Ibuprofen. and Meloxicam.

The side effect of these drugs is expressed in erosive and ulcerative lesions of the stomach and inhibition of platelet formation. In addition to damage to the gastrointestinal tract, nephrotoxic, hepatotoxic, ototoxic and other side effects are also characteristic. To improve the tolerability of the reduced effect on the gastrointestinal tract, it is recommended to combine the use of non-steroids with gastroprotectors, reduce the dose, use enteric-soluble forms, switch to intramuscular, rectal or local administration.

Chondroprotectors

These are products that improve the structure of cartilage. They help strengthen cartilage tissue and thereby slow down the progression of arthrosis. Chondroprotectors are taken in long courses, for at least 3 months. It is necessary to carry out treatment 2 times a year.

Chondroprotectors come in capsules, tablets and powders (Structum, Teraflex, Arthra, Chondrosamine), and in the form of ointments (Chondroitin Akos, Chondroart, Chondroxide). In hospital settings, intra-articular injections of Ostenil and Fermatron are performed. Dietary supplements - Honda protectors ("Honda capsules", "ArthroStopPlus"), in contrast to medicines, have a lower content of active ingredients.

Vitamins and minerals for joint diseases

Vitamin monopreparations are also used in the treatment of arthritis ( folic acid, nicotinic acid, nicotinamide, etc.) or antioxidant complexes (Triovit, Tri-vit, Antioxycaps Neurobex, Neurorubin, Milgamma). Essential Minerals for joint diseases - sulfur, selenium, zinc, manganese, copper, molybdenum. Immunomodulatory drugs are used to treat severe forms of arthritis.

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The demand for such a medication as Paracetamol is understandable due to its wide spectrum of action. The pharmacological agent in question used not only as an antipyretic, but also in a number of other cases. Using Paracetamol, the instructions for use will tell you in which cases these tablets should be taken, and in which cases it is better to abstain, choosing a more effective active ingredient.

Pharmacological effectiveness of the drug and description

A drug belongs to the anilide group medicines , characterized by pronounced analgesic and antipyretic properties. The medicine has a number of unique properties, therefore can be used for various symptoms associated with increased body temperature.

In order not to make a mistake with taking medication for children and adults (what it helps with), you should thoroughly study the instructions (description) included in the box with the medication.

Release form and composition

For ease of use in certain symptomatic cases, the use of the drug is very convenient and practical, due to the variety of the following dosage forms:

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• Pills. Common production option medication. They have a round shape and White color. To make it easier to reduce the dosage, the tablets have a dividing notch. Paracetamol tablets are sold in pharmacies in 10-20 units per standard. The basic composition is paracetamol. In addition, there is the presence of calcium stearate, sodium carboxymethyl starch, and polyvinylpyrrolidol.
• Syrup"Paracetamol". The release form is a viscous transparent liquid of high density with a yellowish tint. The production standard provides for two variations of release, based on volume - 50 or 100 ml. Containers for syrup are glass or plastic bottles Brown, increasing shelf life. In addition to paracetamol itself, the composition contains components such as propylene glycol, riboflavin, ethyl alcohol, aromatic fragrance, sugar and citric acid. The last three substances determine what makes the medicine taste good.
• Suspension. The product is a viscous pink substance with a pronounced fruity flavor. It goes on sale in brown bottles with a capacity of 100 ml. The main active ingredient is paracetamol, supplemented with distilled glycerin, sorbitol, sodium citrate, propylparaben, citric acid, sodium sugar, food coloring. There is no alcohol.
• Candles. The oblong shape is designed for easy rectal administration. Visually they appear white. In a standard package of 5 pieces (100 mg). In addition to paracetamol, the composition contains fatty mass, which does not create suppositories painful sensations upon introduction.

Indications for use

The drug has a wide range of capabilities, facilitating general state body in the following cases:

• Fever. For severe colds, Paracetamol relieves fever. It is advisable to use in cases where the temperature has passed the low-grade level (above 37.5 degrees).
• Headache. They often take Paracetamol for the head, relieving the corresponding negative state within an hour. For prolonged pain, it should be used for no longer than 4 days. Further, the effect decreases due to the body becoming accustomed to the product.
• Dental ailments. In the absence of specialized painkillers, the drug will provide analgesic effect for a couple of hours. Effective for cavity irritations and swollen gums.
• Period of menstruation. Recommended for the prevention of pain associated with the onset of the menstrual period.
• Hangover syndrome. The “broken” state after excessive libation can be eliminated with this drug. Taking Paracetamol for your head can significantly alleviate this condition.
• For acne. Paracetamol helps to cope with inflammatory processes on the skin of the face if inflamed areas due to acne or acne are found. The medicine in tablets should be crushed to a powdery mass, and brought to a paste with a few drops of clean water. The prepared product is used externally by applying the lotion to the irritated skin area.

Contraindications

Along with the positive effects, contraindications should also be studied with a drug such as Paracetamol. The instructions say that The medication should not be used in the following cases:

1. allergic prerequisites to the main component;
2. kidney diseases;
3. liver diseases;
4. infancy is less than 1 month.

In addition, Paracetamol is not allowed during pregnancy, as well as during the lactation period.

Each form of release of the drug has its own strict use. In particular:

• Pills. For adults, 1-2 tablets are recommended depending on the concentration of the main substance (200-500 mg). Take up to 4 times a day with obligatory washing down with water. For children from 3 years old, 1 tablet with a dosage of 200 mg. Daily norm- 2 grams.
• Syrup. Adults are advised to drink four doses per day, 50 ml each. Children's intake is limited to 2.5 to 20 ml no more than four times a day, based on age from 3 months to 12 years (up to 500 mg).
• Candles. Dosage for children from six months to one year - up to 100 mg per day; for children from one to three years - up to 150 mg; for children from 3 to 5 years old - up to 200 mg; from 5 to 10 years - up to 350 mg; for children from 10 to 12 - up to 500 mg. Do not use for more than three days, which may cause addiction to a fragile organism.

special instructions

When taking Paracetamol, the instructions for use include: clause with special warnings in the following cases:

• The presence of alcoholic hypatosis may pose a risk of complications to the liver. In this regard, when using Paracetamol-500 for a long time, it is necessary to monitor the condition of the peripheral blood, periodically undergoing appropriate tests.
• With a prolonged course of treatment with this drug, some complications may occur in patients who have problems with normal kidney function.

Drug during pregnancy

Take Paracetamol during pregnancy, as well as during breastfeeding a newborn baby, strictly prohibited. In cases of urgent need, when Paracetamol-500 cannot be avoided, the child should be weaned from the breast by switching to appropriate dairy products.

The use of Paracetamol during pregnancy early stages possible, but women should remember that the daily dosage should not exceed more than 4 grams. In this case, the course is limited to 4 days. If there are no other non-steroidal drugs at hand, then Paracetamol during pregnancy in the 1st trimester should be taken as follows:

1. limited to three doses per day;
2. You can take half a tablet at one time;
3. Stop taking when the effect is achieved, do not use for prophylactic purposes.

It should be remembered that if Paracetamol is chosen for treatment, it should be taken carefully during pregnancy, preferably under the supervision of a doctor.

Use by children

For the flu or a common cold, it is advisable to give children medication in the form of syrup. Firstly, the liquid-like state of the medicinal substance will be absorbed faster into the walls of the stomach, which means its effect will be more active. Secondly, flavoring additives will allow you to take the syrup without any problems, from which the child will not experience any taste discomfort.

Overdose and side effects

When taking Paracetamol tablets for headaches or fever, you should not exceed the indicated frequency of administration and its concentration. Otherwise, the following consequences are possible:

• Decline in physical tone. The patient experiences a drowsy state.
• Ailments in the stomach area.
• Skin allergies in the form of a red rash or “urticaria” are possible.
• Overload of the kidneys and liver due to intoxication.
• Depletion of blood in hemoglobin, decreased glucose.

In these cases, you should not rely on own strength, whether this happened for the first time or not, you should go to the emergency room.

Interaction with other drugs

• It is possible to use the drug with Nurofen. In this case, the method of application involves alternating each of the means. Such a “tandem” can easily counteract high temperature. If you want to use both drugs together at once, you need to halve their dosage.
• "Nimesulide". It can be used as an auxiliary medication so that there is no addiction to Paracetamol when relieving fever.
• "Diclofenac". The combination of drugs is relevant for rheumatoid arthritis, osteoarthritis, and radiculitis. You should not take it so as not to aggravate ulcers of the gastrointestinal tract, liver and kidneys. Diclofenac and Paracetamol should be avoided during pregnancy.

Cost, storage and dispensing from the pharmacy

The price directly depends on the form of release. In particular:

• Pills. Standard of 10 tablets (dosage 200 mg) – 8-10 rubles; standard of 10 tablets (dosage 500 mg) – 10-15 rubles.
• Syrup. A 100 ml bottle costs from 60 to 150 rubles.
• Candles. A pack of 10 suppositories with a dosage of 50 mg – 80-120 rubles.
• Suspension. A 10 ml bottle can be purchased for 90-130 rubles.

Traditionally, purchased forms of medication should be properly stored in a cool and dark place.

Regardless of the concentration, just like Paracetamol 325, the instructions for use state that the medicine can be dispensed from the pharmacy without any prescription, including for pregnant women.

Pharmaceutical analogues

Effective analogues are such drugs as:

• "Panadol". It contains both paracetamol and caffeine. Released in the form of tablets with varying dosages from 500 to 1000 mg. The price is within 70-100 rubles.
• "Daleron." Effectively blocks toothache, lowers fever during colds. Available in the form of a suspension. 100 ml bottle. Cost from 30 to 70 rubles.
• "Apap." Available in tablets with a dosage of 500 mg. Produced in different standards of 6, 12, 24 or 50 pieces. Successfully relieves toothaches and reduces fever. The cost varies in different pharmacies (50-120 rubles).

Reviews

Based on numerous reviews, we can assume that the drug is very popular in the fight against high fever.

Allows pain relief for migraines and dental anxiety.

FAQ

• Use for arthrosis knee joints . Is it possible to cure an illness with Paracetamol? The product perfectly relieves pain, but does not provide treatment.
• Can it help with gout?? Effective when you need to relieve fever. It is an analogue of Aspirin.
• What are the differences and descriptions of imported Paracetamol?? In addition to domestic manufacturers, analogues from Ukraine and the Republic of Belarus are popular. Particularly different in this sense is Paracetamol with a single dose concentration of 325 mg from the Stirol concern. The pills have a rapidly dissolving coating.
• Will it help with my head?? Definitely, the drug helps relieve headaches, especially after an alcohol hangover.
• Can I take it during menstruation?? The drug not only reduces the corresponding pain, but also helps reduce bleeding.
• Is it effective against flu?? The drug reduces body heat, and the influenza virus can be overcome with the help of antibiotics.

Based on the information provided, you should not treat the drug with lukewarmness. It can bring not only relief from certain symptoms, but also cause harm in case of an erroneous overdose.

Pharmacist talks about the drug

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– a non-steroidal anti-inflammatory drug with a pronounced antipyretic effect. Used medication advantage for therapy pain syndrome moderate or mild severity, accompanied by an absent inflammatory process and severe fever and body aches. The product helps well with aching joints and signs of acute respiratory disease. Can be used to relieve headaches, myalgia, neuralgia, painful periods, arthralgia, toothache. Will this medication help with arthritis or arthrosis? To find out the answer to this question, you should study in detail the pharmacological properties of paracetamol.

Pharmacological properties of Paracetamol

Paracetamol is a non-narcotic analgesic substance; it can only conditionally be classified as an NSAID, since it relieves pain, but in fact it is not one. The drug has well-defined antipyretic properties, has a moderate analgesic effect, but has no anti-inflammatory properties at all, which means that the medicine will not help relieve the inflammatory process. The therapeutic effect of the drug is manifested due to the inhibition of inflammatory mediators, as a result of which the sensitive threshold for the perception of pain increases.

With various degenerative and inflammatory processes, paracetamol itself is unlikely to help if they are pronounced. It can be combined with other NSAIDs, which have more pronounced anti-inflammatory properties than paracetamol itself. However, there is one option when this medication can help with joint pain. The fact is that most often an increase in body temperature with initial stages acute respiratory illness is accompanied by severe aches in the joints and muscles. This aching feeling closely resembles that a person has sore knees or other parts of the body. As soon as you take literally 1-2 tablets of paracetamol, your body temperature begins to decrease and disappears along with it unpleasant feeling in the bones.

From the above, we can conclude that paracetamol will help with joint pain, but not of an inflammatory nature, but associated with impaired control of the body’s thermoregulation in response to the appearance of a viral agent in the patient’s body. Many people will be interested in the question: which NSAIDs are best suited for combating degenerative-inflammatory joint pain?

NSAIDs with pronounced anti-inflammatory properties

Arthritis is an infectious inflammation of the joint, which, in addition to basic therapy, requires symptomatic therapy to eliminate the source of inflammation and reduce pain. Arthrosis - chronic pathology joint, which is accompanied by limited mobility and deformation that interferes with normal motor activity. Accompanied by arthrosis severe pain, a feeling of stiffness, especially in the morning. In addition to basic therapy, this disease requires the use of NSAIDs for pain relief and inflammation.

List of medicines suitable for symptomatic therapy arthritis and arthrosis:

• – a non-steroidal drug with pronounced analgesic and anti-inflammatory properties, available in the form of a gel for external use, it helps well in the presence of articular syndrome, with regular use it reduces the feeling of stiffness in the morning, removes swelling, and eliminates pain.
• Diclofenac sodium is a universal drug that equally has pronounced anti-inflammatory and analgesic properties. It can be used to treat pain of any location, not just in the joints. There are many forms of release, ranging from tablets, ointments and injections, to rectal suppositories, transdermal patches and aerosols.
• – a non-selective non-steroidal anti-inflammatory drug, which is prescribed primarily for the treatment of pain due to degenerative processes in the joints. Available in tablet form and rectal suppositories, but due to the strong severity of side effects on gastrointestinal tract, is not the first choice.
• Indometacid is an NSAID in tablet form that has the most pronounced anti-inflammatory effects and moderate analgesic properties. Despite these qualities, it is rarely prescribed due to the severity of side effects on the digestive system.
• Movalis is a selective NSAID with moderate anti-inflammatory and analgesic properties. Due to the selective effect on pain centers, it can be used for a long time, unlike non-selective analogues. Considered one of the the best drugs for the treatment of joint pain.